5. Colts vs. Patriots (2006)
Tom Brady has been involved in some classic quarterback duels and usually, he is the winner. The New England Patriots were a clinical winning machine for most of his tenure. However, there were exceptions as this game proves. He met his match in Peyton Manning in the 20006 AFC Championship. This didn’t seem likely because the Pats led 21-3 at one point (via Fansided).
The Colts showed great heart because they rebounded from a pick-six and scored 18 straight points. Finally, the fans had a game that they will never forget. Manning recovered from his earlier mistake and threw multiple touchdowns. Meanwhile, Brady had one of the few major costly blips of his career. An interception ended the game as well as New England’s hope of a Super Bowl appearance.