
22. Lloyd Carr (2007)
Carr is a member of the college football Hall of Fame. The former Michigan Wolverines coach led his team to national championships. However, he also fell victim to one of the biggest upsets ever seen in gridiron football. Michigan played the unranked Appalachian state in Carr’s final season. Nobody gave Jerry Moore’s men a chance, but they produced an incredible result.

It was only the second time in history that an FCS team overcame a ranked FBS team. While Appalachian State had pedigree, it was still a magnificent result. Michigan has a massive football program while its opponents were a tiny school. Meanwhile, they traveled to Ann Arbor for the game. This made it even more painful for Michigan because they suffered one of their worst defeats on home soil.