Adrian Peterson
Peterson is one of the greatest running backs ever and overcame adversity along the way. One of the most incredible parts of his impressive career was when he bounced back from injury in 2012. An ACL and MCL tear brought the previous season to an early end for him.

Most running backs take over a year to recover from ligament injuries and are never the same again. However, Peterson made a mockery of this when he started the new season and almost broke the rushing yards record. He won the MVP award for his efforts in a magnificent year (via Deadspin).