11. Anthony Joshua vs. Andy Ruiz 1
Coming into this one, nobody expected anything from Ruiz, a last-minute replacement for Jerrell ‘Big Baby’ Miller. Short and chubby, Ruiz stood in stark contrast to WBO, WBA, IBF and IBO champion Joshua. The first knockdown came in round three when Joshua put Ruiz down. But then the challenger stunned the world.
He unleashed a barrage of punches to knockdown Joshua who rose unsteadily to his feet. Then he knocked him down for a second time at the end of the round. The finish came in the seventh round when Ruiz upset Joshua with a TKO victory. It was one of the biggest shocks in heavyweight history.