18. New York Giants vs. San Francisco 49ers
All he could do was hold his head in disgust. Kyle Williams made two crucial mistakes against the Giants, with the second one costing his team the 2012 NFC Championship Game. Williams was on ball-handling duties when destiny’s cruel hands sunk its claws into him.

Williams was on punt duties when he mishandled twice. First of all, he allowed the Giants to bring the game to overtime. Then he dropped the ball again, allowing Lawrence Tynes to score the winning 31-yard field goal. It was a miserable way for the game to finish for the young man.