Newton’s Second Fumble
The Panthers had one of the best offenses in the league throughout 2015 when they reached Super Bowl 50. Meanwhile, Denver’s defense led them to the showpiece event so it was a fascinating clash on paper. In the end, the Broncos pulled off the victory as Peyton Manning retired with a second ring. But it was a lost opportunity for the Panthers and Cam Newton.

Newton entered the game as the new regular season MVP after an electric season. However, he made a couple of big errors in this clash. Two fumbles cost his team dearly and gave Denver momentum. The second was one of the biggest Super Bowl mistakes ever because Denver immediately scored a touchdown (via Colorado Public Radio).