Many people like to argue that Brady isn’t the greatest quarterback ever. They’ll point at the achievements of Aaron Rodgers, Joe Montana, or Peyton Manning. The latter had a fantastic record against the former Patriots star. Indy defeated New England twice in 2009 including in the AFC Championship game (via Fansided).
However, their final on-field meeting seriously embarrassed Brady. The Broncos faced the Patriots in the 2016 AFC title game. Brady finished the game with two picks and a garbage 48.2 completion percentage. Manning also had a terrible play on the way to his second ring. But the Denver defense kept him out of QB jail.