Notre Dame def. UCLA – 1974 NCAA regular season:
Legendary coach John R. Wooden led the Bruins to the most dominant NCAA basketball run in history. Having secured an unreal seven straight national titles, UCLA also won 88 straight games from 1971-74.
Yet the run came crashing down when they battled Notre Dame in 1974. The Bruins would go on to lose four games that season. It was a letdown that they only finished third in the NCAA that year, a testament to their greatness.