6. Middle Tennessee vs. Michigan State (2017)
They call it March Madness for a reason. Middle Tennessee brought this to the next level against the Spartans in 2017. Michigan State was the second-favorites to win the entire tournament. But the Blue Raiders sent them home early in one of NCAA Basketball’s biggest upsets ever.
Tom Izzo was one of the most experienced coaches in the sport but he couldn’t save his team from humiliation. The No. 15 seeds won 90-81 and upset gamblers all across the world (via USA Today). However, they instilled joy in the hearts of every watching neutral because this is what fans love to see.