16. VCU vs. Kansas (2011)
Even VCU students didn’t expect to make the NCAA tournament. But that’s exactly where they found themselves in 2011 despite a patchy season. Nobody expected much from the Rams but they went on a roll. They launched a series of upsets as they defeated USC, Georgetown, and Purdue before a clash with Kansas.
Then, they met the Kansas Jayhawks in Elite Eight. This was supposed to be the end of their magical run. However, they overcame the No.1 seed in style (via Sporting News). They won the game by 10 points and inspired other schools in the process. Even though they eventually lost to Butler, they still defeated ‘better’ teams from five conferences.