Seahawks 58 – Cardinals 0 (2012)
This blowout was one of the biggest beatdowns of the past decade. The Cardinals didn’t know what happened as Seattle dominated them. They couldn’t do anything right as the Seahawks defeated them in every aspect of the game. It’s rare for even the worst teams to suffer this type of crushing loss.
Arizona turned the ball over eight times to hand Seattle the initiative. They had an insurmountable hill to climb at half-time because the score was 38-0. But they couldn’t get any points on the board as they went down to one of the worst losses in franchise history (via Arizona Sports).