17. Notre Dame vs. Texas Tech (1998)
Texas Tech became a powerhouse in 1993 after winning their first NCAA Tournament. They consolidated and progressed over the next few years. Nobody gave the Fighting Irish a shot against them in the 1998 installment. But Notre Dame overcame the odds to oust their opponents.

Ruth Riley was the star of the show after scoring 23 points in the second half. Amazingly they also won this game on Texas Tech turf (via Orlando Sentinel). This was against the odds because Notre Dame was 0-5 against ranked opponents that season. That’s the joy and pain of March Madness.